中医药研究论丛

254.2 中药介入治疗对新冠肺炎重症疗效评估
TJ TCM.25(4) : 15-26, 2022 15
DOI : 10.6516/TJTCM.202212_25(4).0002

 

中药介入治疗对新冠肺炎重症疗效评估
Evaluation of the Curative Effect on Traditional Chinese Medicine
in Severe Coronavirus Disease (COVID-19)
周仁杰1 庄佳颖1 陈智圣1,3 罗子尧1 王人澍1,2*
1 佛教慈济医疗财团法人台中慈济医院中医部,台中,台湾
2 慈济大学学士後中医学系,花莲,台湾
3 童综合医疗社团法人童综合医院,沙鹿院区中医科,台中,台湾
【摘要】
背景:新型冠状病毒肆虐全球,该病毒不仅有高传染力,感染後亦有较高的重症机率,因此西医或中医皆朝着能够有效抑制病毒繁殖和减少重症的方向努力。受Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)感染的患者中,存在高炎症反应及免疫抑制的状况,根据先前中医以中药治疗SARS 的经验,发现中药具有抗发炎、抗病毒及免疫调节的特性,因此适当的中药介入对於治疗新冠肺炎患者能有一定程度上的效果。
方法:本研究描述了7 名由台中慈济医院收治入院的COVID-19 重症患者,均
接受西医常规治疗,其中有5 名同时接受中医药物治疗。
结果:中药介入治疗组与无中药介入治疗组相比,在症状缓解速度(住院天数)及病毒量衰退速度(病毒筛检阳性转阴性或Cycle Threshold 值< 30 的时间),相较於无中药介入有更佳的表现。
结论:在COVID-19 重症住院患者中,中药治疗搭配西医常规治疗与单纯西医常规治疗相比,有较能缓解症状及增快病毒衰退速度的趋势,差异并不是非常显着,可能受限於研究族群过小,若未来能有更多更大型的相关研究,相信可以更看出中药介入COVID-19 重症患者的有效性。
【关键词】新型冠状病毒、中医、中药、症状缓解、病毒量衰退速度
Ren-Jie Chou1Chuang Chia-Ying1Chih-Sheng Chen1,3
Zi-Yao Luo1Jen-Shu Wang1,2*
1Department of Chinese Medicine, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical
Foundation, Taichung, Taiwan
2School of Medicine, Tzu Chi University, Hualien, Taiwan
3Tungs’ Taichung Metroharbor Hospital, Shalu Campus, Department of Traditional Chinese
Medicine, Taichung, Taiwan
【Summary】
Background: The new coronavirus is raging around the world. This virus is not
only highly infectious, but also has a high mortality rate once humans are infected.
Therefore, both Western and Chinese medicine are trying to find effective drugs,
which can block the reproduction of the virus and prevent the COVID 19 patients
progressing to severe illness. Patients infected with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) have a high inflammatory response and
immunosuppression in the clinical course. According to the previous experience of
the treatment against SARS, it has been found that Traditional Chinese Medicine
has anti-inflammatory, antiviral and immunomodulatory properties. Therefore,
appropriate treatment with Traditional Chinese Medicine have great opportunity to
help COVID 19 patients accelerate recovery.
Method: We describe a series of seven patients who were tested positive and
admitted to Taichung Tzu Chi Hospital. After admission, they were all classified as
severe illness according to their clinical conditions. Two of them (control group)
were only treated with standard Western medicine at Taichung Tzu Chi Hospital,
and five of them treated with standard Western medicine combined with Chinese
Herbal Medicine (CHM).
Results: Among the 7 severely ill patients admitted to this hospital, the CHM group
compared with the control group, not only the speed of symptom relief (days of
hospitalization) but the speed of virus decline (virus screening time from positive
to negative or Cycle Threshold value < 30) are better than the control group. If
compared with other antiviral drug related papers, good curative effects can be
obtained in the above two indicators. Only in terms of the speed of symptom relief,
there is still room for improvement when discussing with China’s TCM formula-
Qingfei Paidu decoction against COVID 19.
Conclusion: Chinese Herbal Medicine against COVID 19 can significantly shorten
the duration of hospital stay and virus decline.
【Keywords】SARS-CoV-2 virus; Traditional Chinese Medicine; Chinese Herbal Medicine; symptom relief; the speed of virus decline