中医药研究论丛

232.7 结合中西医理论探讨新冠肺炎的病程进展及治疗展望
TJ TCM.23(2) : 93-116, 2020
 
结合中西医理论探讨新冠肺炎的病程进展及治疗展望
Exploring the Progression and Treatment Prospects of Coronavirus Disease 2019
(COVID-19) with the Integration of Traditional Chinese and Western Medicine   
黄靖钧1# 吴孟珊2# 陈忠仁3*
1 高雄医学大学附设中和纪念医院中医部,高雄,台湾
2 天主教圣功医疗财团法人圣功医院中医部,高雄,台湾
3 高雄市立大同医院(委托高医经营)内科部,高雄,台湾
【摘要】
严重特殊传染性肺炎Coronavirus disease 2019(COVID-19)是由一种新型冠状病毒SARS-CoV-2 所引起的疾病,已成为世界各国目前迫切需要解决的医疗问题。对於COVID-19,整合中西医的相关研究,运用中医理论来进行分析探讨中医药所能扮演的角色是本篇文章的核心价值。
本文对於COVID-19 的论述主要根据近期发表的研究文献,从流行病学、病毒学、临床症状和西医治疗概略说明,再进入中医对此疾病的认识,依照病程轻重结合卫气营血的传变推论病因病机,并运用现代医学的研究成果加强以上中医的论述。卫分属COVID-19 发作初期的免疫反应;气分属正邪相争达免疫高峰期;营分属血管内皮功能异常;血分属凝血障碍造成血栓或弥漫性血管内凝血。
最後在文献实证的基础下,探讨中医治疗用方,病程在轻、中症属卫、气分,可选用银翘散、桑菊饮或麻杏甘石汤,病程进入重危症属营、血分,治疗以西医为主、中医为辅,可使用安宫牛黄丸、生脉散或犀角地黄汤。期待中西医学的合作,有助於提升新冠肺炎的治疗效果及预後。
【关键词】新冠肺炎、新型冠状病毒、卫气营血
 
Ching-Chun Huang1Meng-Shan Wu2Chung-Jen Chen3*  
1Department of Traditional Chinese Medicine, Kaohsiung Medical University Chung-Ho
Memorial Hospital, Kaohsiung, Taiwan
2Department of Traditional Chinese Medicine, St. Joseph Hospital, Kaohsiung, Taiwan
3Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan
【Summary】
Coronavirus disease 2019 (COVID-19) is a disease caused by a new coronavirus SARS-CoV-2, and has become an urgent medical problem needed to be resolved all over the world. The core value of this article was to integrate relevant research on Traditional Chinese medicine (TCM) and Western medicine (WM), and analyzed as well as explored the role that TCM can play by the theory of TCM.
The thematic discussion about COVID-19 was mainly based on the recently published research literature. The article started from the general description of epidemiology, virology, clinical symptoms and WM treatment. Then, we discussed the viewpoint of TCM on COVID-19 and inferred the etiology and pathogenesis according to the severity of the progress of COVID-19 and the transmission of Wei, Qi, Ying, and Xue. In addition, we took advantage of modern medical research to strengthen the above paragraph. We described Wei as part of the immune response in the early stage, Qi as part of struggling between the vital energy and the pathogenic factor to reach the peak of immunity, Ying as part of vascular endothelial dysfunction and Xue as part of blood coagulation disorder such as thrombosis or diffuse intravascular coagulation (DIC).
Finally, on the basis of evidence-based literature, we discussed the prescriptions of TCM. The mild and moderate stages of the disease could be defined as Wei and Qi, which could be prescribed Yin Qiao San, Sang Ju Yin or Ma Xing Gan Shi Tang. In the critical stage of the disease which could be defined as Ying and Xue, we could use An Gong Niu Huang Wan, Sheng Mai San or Xi Jiao Di Huang Tang for adjuvant therapy. It is expected that the cooperation between TCM and WM will help to improve the therapeutic effect and the
prognosis of COVID-19.
 
【Keywords】COVID-19, SARS-Co-V-2, Wei, Qi, Ying, and Xue