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202.16 肺癌标靶药物副作用之中医治疗病例报告

肺癌标靶药物副作用之中医治疗病例报告

A Case Report of Traditional Chinese Medicine Treatment in Side Effect of Target Therapy for Lung Cancer

陈嘉允1*

1 财团法人彰化基督教医院中医部，彰化，台湾

【摘要】

肺癌为全球癌症致死原因之首位，在台湾从1982 年起，恶性肿瘤便成为为国人十大死因之首，而其中肺癌在恶性肿瘤死亡原因当中更是名列前茅。近年来因为空气品质恶化的关系，肺癌的死亡率有逐渐增加的趋势。肺癌的治疗方式则依癌细胞种类与癌症分期有不同原则。现代医学对於肺癌的治疗除了外科手术切除外，尚有放射线治疗、化学治疗以及标靶治疗。而这类标靶药物主要的副作用为皮疹、痤疮、甲沟炎等皮肤表皮的症状，但一般症状都轻微，而间质性肺炎的发生率不高，但一旦变严重者则可能致命。

本病例报告为56 岁肺癌病患，罹患肺癌使用标靶药物治疗，但因标靶药物副作用影响皮肤，面部及躯干皮肤反覆红疹脱屑，服用高剂量类固醇药物以及抗组织胺药物控制，因为皮肤症状仍难以控制，故至本院中医部寻求治疗。在服用中药控制後，逐渐不需服用西药，面部症状也获得良好控制，因国内期刊没有关於使用中医治疗肺癌标靶作用副作用的病例，故整理此医案作为治疗肺癌使用标靶药物导致皮肤副作用的临床叁考。

【关键词】

肺癌、标靶药物、皮疹、中医

Chia-Yun Chen1*

1Department of Chinese Medicine, Changhua Christian Hospital, Changhua Christian

Medical Foundation, Changhua, Taiwan

【Summary】

Lung cancer is the major cause of death worldwide. In Taiwan, malignancy is the leading cause of death since 1982. Lung cancer in which the cause of death is the top of the cancer is among the best. In recent years, because of the air pollution, the mortality rate of lung cancer has gradually increased. The treatment of lung cancer is different according to the type of cancer cells and cancer staging. The treatment of lung cancer In addition to surgical resection, there are radiation therapy, chemotherapy and target therapy. The main side effects of such target drugs for the skin rash, acne, paronychia and other skin epidermis symptoms. The 56-year-old patients was a lung cancer patient who suffering from lung cancer using target therapy, but the side effects affect the skin, facial and trunk skin repeated rash scaling. The patient took high-dose steroids and antihistamine but symptoms are still difficult to control, so she search the treatment of Traditional Chinese Medicine. After taking the Traditional Chinese Medicine, she gradually recovered without taking steroids and anti-histamine. Because there was no case report about treating the symptoms of lung cancer target therapy side effects. We presented this case for clinical reference.

Keywords： Lung cancer, Target therapy, Dermatitis, Traditional Chinese Medicine

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