中医药研究论丛

202.14 保和丸於胰脏恶性肿瘤末期运用之病例探讨

 

保和丸於胰脏恶性肿瘤末期运用之病例探讨
Treatment of Advanced Pancreatic Carcinoma Patients with Baohe Pills: A Case Report
廖翊芳1 陈金女2 赖荣年1,3,4*
1 中国医药大学中医学系,台中,台湾
2 中国医药大学中西医结合研究所,台中,台湾
3 中国医药大学附设医院中西医结合科,台中,台湾
4 台湾中医家庭医学医学会,台北,台湾
【摘要】
胰脏恶性肿瘤的61 岁女性,分析其癌症末期死亡前318 天的就诊用药,接受中西医合并治疗共58 日,在病患肾丝球过滤率下降到69 的时候,服用39 天的保和丸共248 公克,肾丝球过滤率上升到96。显示中西药并用不但没有肾脏毒性的交互作用,而且保和丸在胰脏癌末期可能具有保护肾丝球免於损害的保护作用,结论:胰脏恶性肿瘤末期的病患如果肠胃功能不好、食欲不振,保和丸为一安全可以搭配并服用的中药方剂。
【关键词】
保和丸、胰脏恶性肿瘤、肾丝球过滤率
 
Yi-Fang Liao1 Chin-Nu Chen2 Jung-Nien Lai1,3,4*
1School of Chinese Medicine, China Medical University, Taichung, Taiwan
2Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan
3Department of Integrated Chinese and Western Medicine, China Medical University
Hospital, Taichung, Taiwan
4Taiwan Association for Traditional Chinese Medicine of Family, Taipei, Taiwan
【Summary】
We would like to report for what TCM practitioners may experience as a 61-year-old female patient goes through the end stages of pancreatic cancer. The retrospective chart was reviewed and we found that she received 58-day traditional Chinese herbal products in 318-day medical record before her death. Interestingly, her estimated glomerular filtration rate (eGFR) was from 69 mL/ min/1.73 m2 to 96 mL/min/1.73 m2 after taking 248-gram of Baohe pills (totally 39 days). This result infers that Baohe pills might be a safe choice in treating gastrointestinal upset for pancreatic patient who were receiving nephrotoxic chemotherapeutic regimen.
Keywords:Baohe pills, Pancreatic cancer, Glomerular Filtration Rate