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中医药研究论丛
 201.5三伏贴之文献回顾与实证医学研究
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三伏贴之文献回顾与实证医学研究
Sanfutie: A Comprehensive Review of Acupoint Herbal Patching Therapy for Allergic Diseases
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张琼心1 张心宁1,2 黄泽宏1,2 叶沅杰1,3*
1 长庚医疗财团法人基隆长庚纪念医院中医科，基隆，台湾
2 长庚大学临床医学研究所，桃园，台湾
3 国立阳明大学生命科学院分子医学博士学位学程，台北，台湾
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【摘要】
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三伏贴为目前国内常见之中医治疗过敏性疾病的方法，为中医外治法之体现。由於台湾地处亚热带，气候温暖潮湿，过敏性疾患包含气喘、过敏性鼻炎等盛行率居高不下，坊间多以三伏贴等穴位贴敷治疗，於一年中盛夏转秋之际进行三次穴位贴敷的疗程。三伏贴是以《黄帝内经》中「冬病夏治」的概念，以刺激性药物调成膏状，贴敷於穴位之上，而达到调节免疫系统，降低过敏性疾患发作频率及严重度的效果。国内外实证医学证实，穴位贴敷对於过敏性鼻炎、气喘及慢性阻塞性肺病之疗效显着。药物动力学试验亦证实，在穴位及非穴位处进行贴敷，其药物浓度亦有差异。唯对於在「三伏天」进行穴位贴敷，是否相对於其他时间贴敷更为有效，尚无相关研究证实。目前有关三伏贴的研究亦多局限於过敏性疾患，未来仍需更严谨的动物模型试验确立机制，藉以扩增适应症范围。
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【关键词】
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三伏贴、天灸、穴位贴敷、过敏性鼻炎、慢性阻塞性肺病
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Chiung-Hsin Chang1 Hsin-Ning Chang1,2 Tse-Hung Huang1,2 Yuan-Chieh Yeh1,3*
1Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan
2Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung
University, Tao-Yuan, Taiwan
3Program in Molecular Medicine, School of Life Sciences, National Yang Ming University,
Taipei, Taiwan
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【Summary】
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Sanfutie is a special form of acupoint herbal patching therapy performed topically with irritating herbs in the “dog days” to optimize therapeutic effects. According to the literature, Sanfutie can be used to treat various allergic diseases. Currently, there is encouraging evidence for Sanfutie treating respiratory diseases, including allergic rhinitis, asthma, and chronic obstructive pulmonary disease （COPD）. Some published clinical trials or reviews concluded that Sanfutie can improve symptoms and quality of life of allergic rhinitis, and reduce the attack frequency of asthma and COPD without severe adverse effects. Two researches investigated the possible immune-modulating mechanism of acupoint herbal patching. However, clinical trials comparing acupoint herbal patching performed in the dog days and non-dog days are still lacking. Moreover, no study evaluates the efficacy of Sanfutie in treating allergic diseases other than respiratory system. More researches focusing on the mechanism and the relations between climate and efficacy are required to benefit future clinical practice.
Keywords：Sanfutie, Tianjiu, Acupoint herbal patching, Allergic rhinitis, Chronic obstructive pulmonary disease
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