|
Objective: Channel tropism which is an important component of the property of Chinese Medicine is considered the selective therapeutic effects of a single medication on specific zang-fu organs. This article is mainly discussed about the origin, evolution, application, modern research, and future development of channel tropism theory.
Method: This study was collected the literatures related the ten-year database of channel tropism development and modern research in the Chinese Medical Journal Network and PubMed.
Results: According to the literatures of channel tropism, most academics approve channel tropism originated from the description of five flavors, five phases and zang-fu organs in Huangdi Neijing and the statement of the property of Chinese Medicine in Shennongs Classic of Materia Medica. Zhang Zhongjing in Eastern Han Dynasty created syndrome differentiation of six meridians and syndrome differentiation of zang-fu which had far-reaching influence on the formation of channel tropism. Sun Simiao systematically integrated the syndrome differentiation of zang-fu and treatments, revealing the model and concept of channel tropism in Tan Dynasty. In Jin Dynasty, Zhang Yuansu officially used channel tropism theory to describe the property of the medication in Chinese medicine. Wang Ang in Qing Dynasty fully developed the channel tropism theory and proposed channel tropism theory of Chinese medicinal formulae, enhancing the importance of channel tropism theory. Modern academics analyzed the active compound, trace element and proposed receptor theory to verify channel tropism theory.
Conclusion: Channel tropism theory, as a precision medicine in Chinese medicine, developing from accumulating clinical practices of ancient physicians, is not only the reference criteria for clinical application, but also precious culture of Traditional Chinese medicine. How to use modern technology to connect channel tropism theory to clinical Chinese medicinal formulae application providing more precision medicine of the Traditional Chinese medicine is the goal of Chinese medicine profession.
Keywords：the origin of channel tropism, property of Chinese Medicine, precision medicine
|
221.4 中医药物归经理论发展与现代研究
